Liverpool secured a dominant win over West Ham, while other Premier League matches saw Brentford edge Burnley in a seven-goal thriller and Everton secure a late victory against Newcastle.
Burnley secured a return to the English Premier League amid joyous scenes at Turf Moor on Monday when a 2-0 home victory over Wigan Athletic sealed automatic promotion from the Championship.
Chelsea striker Tammy Abraham scored a late opportunist double to secure a 3-0 home win for Chelsea over West Ham United in the English Premier League on Monday.
Manchester City squandered a gilt-edged opportunity to close the gap on Premier League leaders Chelsea when they let slip a two-goal lead to draw 2-2 at home to struggling Burnley on Sunday.
Images from EPL matches played on Wednesday.
Champions Liverpool suffered a shock 1-0 defeat to lowly Burnley on Thursday, ending their 68 match unbeaten home record in the Premier League as their title defence continued to fade.
But for third-placed Spurs, who trail leaders Manchester City and Liverpool by five points, this may prove to be a loss that leaves them with too much ground to make up.
Liverpool started the ball rolling with a convincing 4-1 win at home to promoted Norwich and City responded a day later with an even more emphatic 5-0 victory at West Ham United.
Jose Mourinho tried to conceal his obvious anger at the incidents which he clearly believed had cost Premier League leaders Chelsea victory over Burnley on Saturday.
Liverpool kept their push for a top-four finish in the Premier League on course as Emre Can thundered home a second-half winner to complete a hard-earned 2-1 comeback win over Burnley at a relieved Anfield on Sunday.
Ben Johnson and Tomas Soucek scored second-half goals as West Ham United twice came back from a goal down to earn a 2-2 draw at home to Brighton and Hove Albion in the Premier League on Sunday.
The draw pushed Chelsea up a place into fourth spot in the Premier League, level on points with third-placed Spurs and one point ahead of Arsenal, both of whom have a played a game less.
IMAGES from the Premier League matches played on Saturday.
Arsenal snatched a dramatic 2-1 victory over Burnley to keep their title hopes on track after the referee Jon Moss awarded penalties to both sides and sent off home manager Arsene Wenger in injury time.
Burnley's 0-0 draw at home to Tottenham Hotspur in the Premier League on Sunday completed a profitable weekend for the three clubs bidding to avoid a swift return to the second tier of English football.
Premier League leaders Chelsea moved 10 points clear at the top on Sunday despite being held by Burnley in an entertaining game played amid flurries of sleet and snow.
Raheem Sterling scored a hat-trick as champions Manchester City made a convincing start to their title defence with a 5-0 win over West Ham United.
Burnley reached the Europa League third qualifying round with a 3-1 win over Aberdeen after extra time at Turf Moor on Thursday but now face another tough battle to increase their squad size.
Son fires Spurs to 2-0 win over Huddersfield
A summary of Thursday's matches in the English Premier League.
Chelsea were declared the "autumn champions" by coach Jose Mourinho as they maintained their unbeaten start to the season with a 2-1 win at Anfield on Saturday that kept them four points clear of Southampton at the top of the Premier League.
News of all that's transpired on and off the football field.
Bahader had previously told media he was 75, which he attributed to "rounding up".
Manchester United have scored 14 goals and earned maximum points from their four matches under interim boss Ole Gunnar Solskjaer.
Chelsea and Manchester City tightened their stranglehold on the Premier League title race on Saturday, recording victories over struggling clubs to stretch further clear of their increasingly forlorn pursuers.
Chelsea are 10 points clear at top of the English Premier League championship table.
A stoppage-time goal from Martin de Roon earned Middlesbrough an unlikely 1-1 draw at Premier League leaders Manchester City on Saturday.
Images from the English Premier League matches played on Sunday
Manchester City suffered their first home Premier League loss in eight months as a shock 3-2 defeat by Crystal Palace on Saturday left Pep Guardiola's champions trailing leaders Liverpool by four points.
West Ham United could face repercussions after several pitch invasions and ugly scenes in the stands during the second half of a crushing 3-0 home Premier League defeat by Burnley on Saturday.
Former Cup winners Coventry, now plying their trade in the bottom division of the Football League, revived memories of happier times as Jordan Willis and Jack Grimmer scored the goals in a 2-1 victory at the Ricoh Arena.
Chelsea's new signing Gonzalo Higuain netted his first two Premier League goals in Chelsea's 5-0 thrashing of Huddersfield Town while Tottenham Hotspur's Son Heung-min struck late for a 1-0 win over Newcastle United as they moved into second place.
Images from the English Premier League matches played on Sunday
Images from the English Premier League matches played on Sunday night
News of all that's transpired on and off the football field
Jermain Defoe made himself an instant Sunderland hero with a sensational volleyed goal to seal a vital 1-0 win over North East rivals Newcastle United in the Premier League on Sunday.
Ten-man Arsenal suffered a 3-0 Premier League defeat at Leicester City on Sunday in another blow to their hopes of finishing in the top four and qualifying for the Champions League.
Images from the English Premier League matches played across England on Tuesday
Second-half goals from Leroy Sane and Raheem Sterling stunned Arsenal at the Etihad Stadium on Sunday as Manchester City came from behind to win 2-1 and move seven points behind leaders Chelsea.
Reigning champions Manchester City took the lead after 24 seconds but suffered a shock 2-1 defeat at Newcastle United.